New advance of research on therapy of severe acute radiation sickness with mesenchymal stem cells.
- Author:
Ling-Ling GUO
1
;
Ming LI
;
Shuang XING
;
Qing-Liang LUO
Author Information
1. School of Radiation Medicine and Public Health, Suzhou University, Suzhou 215123, Jiangsu Province, China.
- Publication Type:Journal Article
- MeSH:
Acute Radiation Syndrome;
surgery;
Humans;
Mesenchymal Stem Cell Transplantation
- From:
Journal of Experimental Hematology
2011;19(3):828-830
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSC) are a kind of non-hematopoietic adult stem cells with self-renewal and multilineage differentiation potential, which have special biological characteristics, such as secreting various cytokines, promoting hematopoiesis, accelerating stem cells homing and reconstructing hematopoietic microenvironment. MSC are collected and amplified easily, and can be transfected by exogenous gene. Many reports indicated that MSC were applied in therapy for variety of tissues and organs injury, meanwhile the treatment for acute radiation sickness has made significant progress. In this review, the biological characteristics and new research advance on MSC in treatment of severe acute radiation sickness are summarized and discussed.
