Safty action of heat shock protein 27 in reperfusion after spinal marrow ischemia.
- Author:
Jian-Ping XU
1
;
Wen-Rong GUO
;
Guo-Bing LIN
Author Information
1. Department of Orthopaedics, the First Affiliated Hospital of Fuzhou General Hospital of Nanjing Military, Putian 351100, Fujian, China. xjp2001-123@163.com
- Publication Type:Journal Article
- MeSH:
Apoptosis;
HSP27 Heat-Shock Proteins;
physiology;
Humans;
Nitric Oxide;
biosynthesis;
Reperfusion Injury;
prevention & control;
Spinal Cord;
blood supply
- From:
China Journal of Orthopaedics and Traumatology
2012;25(10):880-882
- CountryChina
- Language:Chinese
-
Abstract:
Heat shock protein 27 belongs to the heat shock protein family in the small molecular weight family. This review collected a number of literature to analyze the expression meaning and mechanism of HSP27,expounded HSP27 with inhibition of NO production, maintenance of cell protein stability and accelerated cell damage repair function. At the same time, HSP27 also has a resistance to apoptosis, protecting mitochondria, inhibiting activation of nuclear factor and other related functions. The heat shock protein 27 has protection in spinal cord ischemia-reperfusion.
