Protein microarray biosensor based on imaging ellipsometry and its biomedical applications.
- Author:
Yan-Yan CHEN
1
;
Gang JIN
Author Information
1. National Microgravity Laboratory, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, China.
- Publication Type:Journal Article
- MeSH:
Biosensing Techniques;
methods;
trends;
Humans;
Protein Array Analysis;
methods;
trends
- From:
Acta Academiae Medicinae Sinicae
2006;28(4):596-599
- CountryChina
- Language:Chinese
-
Abstract:
A protein microarray biosensor based on imaging ellipsometry has been developed as a high-throughput and fast technique for protein analysis. As an automatic technique, it has advanced properties such as label-free, multi-protein simultaneous detection, static or kinetic analysis for protein interaction, and qualitative or quantitative analysis. It has been used for the biomedical applications including tumor markers detection, hepatitis B test, protein competitive adsorption and kinetic visualization for protein interactions. It have demonstrated promising potential for further applications in biomedicine.
