Coinfection with HBV and HCV in 128 AIDS patients infected through blood transmission.
- Author:
Yun HE
1
;
Qing-xia ZHAO
;
Ying-jie REN
;
Li-min DING
Author Information
- Publication Type:Journal Article
- MeSH: Acquired Immunodeficiency Syndrome; complications; Adolescent; Adult; Aged; China; epidemiology; Comorbidity; Female; Hepatitis B; epidemiology; Hepatitis C; epidemiology; Humans; Male; Middle Aged; Retrospective Studies; Transfusion Reaction
- From: Acta Academiae Medicinae Sinicae 2006;28(5):662-664
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the clinical features of 128 acquired immunodeficiency syndrome (AIDS) patients infected through blood transmission who were coinfected with hepatitis B virus (HBV) and hepatitis C virus (HCV).
METHODSThe prevalence, liver functions, and some immunological profiles of 128 AIDS patients coinfected with HBV and HCV were retrospectively analyzed.
RESULTSAmong the 128 AIDS patients, 107 (83.6%) were coinfected with HCV, among which 40 (31.3%) patients had abnormal liver functions or liver damage and 15 (11.7%) patients experienced hepatitis symptoms. Three (2.3%) AIDS patients were singly coinfected with HBV, and all of them had abnormal liver functions and hepatitis symptoms. Seven (5.5%) patients were coinfected with HIV/HCV/HBV and none of them had abnormal liver functions or hepatitis symptoms. Eleven (8.6%) patients were only infected with HIV.
CONCLUSIONSThe prevalence of blood-transmitted HIV patients coinfected with HCV is higher than with HBV. The clinical outcomes of HIV coinfection with HCV and HBV are different.