Preparation and characterization of a new injectable bone substitute-carrageenan/nano-hydroxyapatite/collagen.
- Author:
Shao-lei GAN
1
;
Qing-ling FENG
Author Information
- Publication Type:Journal Article
- MeSH: Bone Substitutes; chemistry; Carrageenan; Collagen; Durapatite; Injections; Microscopy, Electron, Scanning; Nanoparticles; Porosity; Surface Properties; X-Ray Diffraction
- From: Acta Academiae Medicinae Sinicae 2006;28(5):710-713
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a new injectable biomaterial carrageenan/nano-hydroxyapatite/collagen (nHAC/Carr) for bone surgery and characterize it.
METHODSnHAC/Carr was developed by filling carrageenan with nano-hydroxyapatite/collagen (nHAC) granules.
RESULTSIt was found that nHAC/Carr had similar X-ray diffraction patterns with that of nHAC. Fourier transform infrared spectroscopy showed that carrageenan did not change its structure in nHAC/Carr. The rheological behavior of nHAC/Carr was the same as carrageenan. The scanning electron microscopy and porosity analysis showed that nHAC/Carr had porous structure and its porosity was about 90%.
CONCLUSIONThe biomaterial nHAC/Carr may be used as an injectable bone substitute.
