Experimental study on different power CO2 laser for vocal cord injury
10.3760/cma.j.issn.1673-0860.2011.12.015
- VernacularTitle:不同功率CO2激光对声带损伤的实验研究
- Author:
Yi ZHANG
1
;
Lu-Hong CAO
;
Qun CHEN
;
Xiao-Ping CHEN
;
Wei-Hua XU
;
Qin FANG
;
Jing-Fei ZHANG
;
Na SUN
;
Guang-Bin SUN
Author Information
1. 上海市浦东新区公利医院
- Keywords:
Vocal cords;
Laser therapy;
Wound healing;
Animals,laboratory
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2011;46(12):1039-1041
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the injury and repair of the subepithelial cordectomy by CO2 laser in different power.Methods Thirty dogs were randomly divided into 5 groups according to different laser power such as A(1 W),B(3 W),C(5 W),D(8 W),E(cold instruments),6 dogs in each group.Subepithelial cordectomy was performed on the dogs and the tissue damage and wound recovery were observed in different time after operation.Results The mucosa reaction in group C,D was heavier than those in group A,B,E,and the wounds healed slowly with visible pathological scars.The densities of fibroblast and blood capillary were determined with optical microscope.It was found that those in group C,D were higher than those in group A,B,E.The difference was statistically significant(average P ＜ 0.05).Observation by electron microscope showed that the injuries were lighter in group A,B,E and there was no significant difference in vocal cord repair process,while the injuries were more serious in group C,D with few elastic fibers in lamina propria and collagen fibers increased significantly after vocal cord repairing.Conclusion The tissue repair after subepithelial cordectomy by CO2 laser with low power(1-3 W)was similar to that by cold instrument surgery.
