Evaluation of a portable device based on peripheral arterial tone in the detection of obstructive sleep apnea.
- Author:
Juan ZHANG
1
,
2
;
Chun-yan WANG
;
Ning-yu WANG
;
Jun-qing LIU
;
Jing-yan DU
;
Guo-xia ZHOU
;
Zhan-feng YAN
;
Xiao-hui WEN
;
Li LI
;
Jin-feng LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Female; Humans; Male; Middle Aged; Monitoring, Ambulatory; instrumentation; Polysomnography; instrumentation; methods; Reproducibility of Results; Sensitivity and Specificity; Sleep Apnea, Obstructive; diagnosis; physiopathology
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(2):112-116
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the accuracy of a wrist-worn device (Watch-PAT 200) in the diagnosis of obstructive sleep apnea syndrome (OSAHS).
METHODSForty-three adult subjects with suspected OSAHS simultaneously had a standard in-laboratory polysomnogram (PSG) and wore the Watch-PAT 200 during a full-night recording. PSG sleep and respiratory events were scored according to standard criteria. The PSG recordings were blindly manually analyzed, while Watch-PAT data were scored automatically based on the algorithm developed previously.
RESULTSThe mean age of the subjects was (42.2 ± 12.2) years (x(-) ± s), and mean body mass index was (28.0 ± 3.9) kg/m(2). Mean PSG apnea hypopnea index (AHI) was (34.9 ± 29.9) events per hour, and mean PAT-AHI was (36.0 ± 29.2) events per hour. There was a significant correlation between PAT AHI and AHI by PSG (r = 0.931, P < 0.01). A Bland-Altman plot of PAT AHI and PSG AHI was also used to assess the accuracy of Watch-PAT 200. At lower levels of AHI, PAT tended to overestimate disease severity, while at higher levels of AHI, Watch-PAT underestimated severity. To assess sensitivity and specificity of Watch-PAT, constructed receiver operator characteristic curves using a variety of AHI threshold values (5, 15 and 30 events per hour). For AHI ≥ 5 events per hour as threshold value, the Watch-PAT diagnosing rate was 93%, and sensitivity as well as specificity were 94.7% and 80.0%. The misdiagnosis rate and missed diagnosis rate were 20.0% and 5.3%. Optimal combinations of sensitivity and specificity for the AHI threshold values (15 and 30 events per hour) were 82.6% and 100.0%, 95.0% and 95.7% respectively.
CONCLUSIONThe Watch-PAT 200 may offer an accurate, robust, and reliable ambulatory method for the detection of OSAHS, with minimal patient discomfort.