Clinical research of 24-hour double-probe pH-metry in the laryngopharyngeal reflux diseases
10.3760/cma.j.issn.1673-0860.2012.04.013
- VernacularTitle:24h双探针pH检测在咽喉反流疾病的临床研究
- Author:
OUYANG-Tianbin
1
;
Shi-Xiong TANG
;
Li-Tao ZHANG
;
Shou-Guo YAO
;
Xu-Qun ZHANG
;
Xu LU
;
Xing CHEN
Author Information
1. 宁波市第一医院
- Keywords:
Hydrogen-ion concentration;
Gastroesophageal reflux;
Diagnosis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2012;47(4):320-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the clinical value of 24 h double-probe pH-mctry for the diagnosis and treatment of laryngopharyngeal reflux (LPR).Methods According to the pH-metry resuhs (whether the reflux events record in the upper esophagus is more than 6.9), patients of refractory pharyngolaryngitis were divided into LPR and control groups (each of 17 cases).All patients treated with anti-acid therapy and conventional pharyngo-laryngitis therapy.Correlation between pH-metry and the reflux symptom index (RSI),the reflux symptom index (RFI) were analyzed.Changes of the RSI and RFI in different group were calculated in post-treatment.Results In the LPR group,the median reflux events of the upright time were higher than the supine time ( Z =- 3.62,P ＜ 0.01 ),but the difference was not discovered in the control group(Z =-0.60,P ＞ 0.05 ).There were no statistical difference between RSI,RSI and RFS with pH-metry,and with moderate concordance ( κ were 0.47,0.53,P ＜ 0.01,respectively).Compared to pre-treatment, the RSI and RFI were decreased both in LPR group and contorl group,Amplitude decreased in LPR group significantly higher than the contorl groups,with statistical difference( t were 3.74,3.01,P ＜ 0.01,respectively).Conclusion The 24 h double-probe pH-metry is significant for the anti-acid therapy of LPR.
