A Case of Primary Non-Hodgkin's Lymphoma Presented as Appendicitis.
- Author:
Jong Dae BAE
1
;
Ho Keun JUNG
;
Ki Hoon JUNG
;
Byung Ook CHUNG
;
Chang Hwa LEE
;
Keon Uk PARK
;
Deuk Young NAH
Author Information
1. Department of General Surgery, Dongguk University College of Medicine, Gyongju, Korea. jgh@dumc.or.kr
- Publication Type:Case Report
- Keywords:
Appendix;
Non-Hodgkin's lymphoma;
Diffuse large B-cell lymphoma
- MeSH:
Abdomen;
Adult;
Appendectomy;
Appendicitis*;
Appendix;
Biopsy;
Bone Marrow;
Diagnosis;
Female;
Gastrointestinal Tract;
Humans;
Lymphocytes;
Lymphoma;
Lymphoma, Non-Hodgkin*;
Thorax;
Tomography, X-Ray Computed;
Ultrasonography
- From:Journal of the Korean Surgical Society
2001;61(6):625-628
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant lymphoma comprise 1~4% of the malignant neoplasms of the gastrointestinal tract (GIT), although primary lymphoma of the appendix is exceedingly rare. Primary non-Hodgkin's lymphoma (NHL) of the appendix reportedly represents 0.015% of all GIT lymphomas. Most cases of primary appendiceal lymphoma have presented with a clinical appearance of acute appendicitis. It is therefore difficult to diagnosis preoperatively. We report a case of primary NHL of the appendix in a 31 year-old female. Appendectomy was performed as a result of the clinical diagnosis of acute appendicitis, due to the rebound tenderness of McBurney's point and a thickend appendiceal wall seen on abdominal ultrasonography. Microscopic examination demonstrated an atypical large lymphoid cell dispersed in a background of small lymphocytes. There were no invading tumor cells on the resection margin. Immunohistochemical studies revealed the large atypical cells stained with B cell marker (CD20), Bcl-6, Ki-67 and UCHL-1 (CD45R0). The post-operative work- up consisted of a CT scan of the abdomen and thorax, a bone marrow biopsy and a gastrofiberscope. These results were normal. No further treatment was recommended. The patient is now 12 months post-operative and doing well.
