Morphological parameters for endothelial cells under shear stress.
- Author:
Xiaoning LI
1
;
Yubo FAN
Author Information
1. Biomechanical Engineering Institute, Sichuan University, Chengdu 610065.
- Publication Type:Journal Article
- MeSH:
Animals;
Biomechanical Phenomena;
Cell Size;
Cells, Cultured;
Endothelium, Vascular;
cytology;
physiology;
Humans;
Intercellular Junctions;
Microscopy, Atomic Force;
Stress, Mechanical
- From:
Journal of Biomedical Engineering
2003;20(3):555-566
- CountryChina
- Language:Chinese
-
Abstract:
Shear stresses acting on vascular endothelial cells due to blood fluid flow play an vital role in regulating their morphology, structure, growth rate and functions. The change in morphology is an instinctive response to biomechanical environment and is an indicator for the functional changes in the cells. In this paper, the morphological research literatures of endothelial cells in the recent years are reviewed and the common morphological parameters are described in detail. At the end, the difficulties of quantitative study of endothelial cell morphology and the future direction of morphological parameters research are also discussed.
