Study of high-intensity electric pulse inhibited sarcoma for improving antitumor drug effect.
- Author:
Hong LI
1
;
Zishu WANG
;
Bisong YUE
;
Fangdong ZOU
;
Kong YANG
;
Jingru SUN
;
Baoyi WANG
;
Hong ZHANG
;
Haichuan CHEN
;
Guo YANG
Author Information
1. College of Life Science, Sichuan University, Chengdu 610064.
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents;
therapeutic use;
Combined Modality Therapy;
Cyclophosphamide;
administration & dosage;
Electric Stimulation Therapy;
methods;
Injections, Intralesional;
Mice;
Sarcoma 180;
pathology;
therapy;
Treatment Outcome
- From:
Journal of Biomedical Engineering
2003;20(4):612-614
- CountryChina
- Language:Chinese
-
Abstract:
This article reports the experiment studies on treating the S-180 sarcomas of KM mice with high-intensity electric pulse and antitumor drug (cyclophosphamide). The results showed that the experimental group of electric field combined with drug has the best effect on tumor, compared with the control group. In addition, electric field can inhibit the formation of vas Capillaries and decrease the supply of nutrition for tumor cell. In conclusion, electric field has inhibited the growth of tumor.
