The advantages of bovine jugular vein tanned with hydrophilia crosslinking agent.
- Author:
En CHEN
1
;
Wenxiang DING
;
Yanan LU
;
Zhuming JIAN
;
Xiaoqing YU
;
Wenyan ZHOU
Author Information
1. Shanghai Research Institute of Congenital Heart Disease for Children, Shanghai 200127, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Bioprosthesis;
Blood Vessel Prosthesis;
Cattle;
Cross-Linking Reagents;
pharmacology;
Glutaral;
pharmacology;
Jugular Veins;
drug effects;
Materials Testing;
Rats;
Rats, Sprague-Dawley;
Tissue Engineering
- From:
Journal of Biomedical Engineering
2004;21(1):66-71
- CountryChina
- Language:Chinese
-
Abstract:
The bovine jugular veins were divided into two groups and treated with 4% EX-313 and 0.5% glutaraldehyde respectively, and then they were examined with naked-eye, microscope and scanning electron microscope. Biomechnics test and dorsal implantation in rats were performed. The aquired data were processed and subjected to t-test. The EX-313 fixed material was more pliable than the glutaraldehyde treated material, and the former had higher anticalcification than the latter. In conclusion, the hydrophilia crosslinking agent EX-313 is superior to glutaraldehyde in treating biomaterials, and the bovine jugular vein tanned with EX-313 should be a promising material for repairing in cardiovascular surgery.
