Efficacy of tongfu mixture for treating post-ERCP pancreatitis: a clinical study.
- Author:
Lin YANG
;
Zhao-Hong SHI
;
Yi-Xi LI
;
Wei HU
;
Yu-Fang WU
;
Jia-Yao YANG
;
Tuo SHI
- Publication Type:Journal Article
- MeSH: Adult; Cholangiopancreatography, Endoscopic Retrograde; adverse effects; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Male; Middle Aged; Pancreatitis; drug therapy; etiology; Phytotherapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2014;34(4):423-425
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the clinical efficacy of Tongfu Mixture (TM) for post-ERCP pancreatitis (PEP).
METHODSTotally 54 PEP patients were randomly assigned to the control group (treated by routine therapy, 26 cases) and the TM treatment group (treated by TM, 28 cases). Clinical indices including the alleviation time of abdominal pain/distention, gastrointestinal function recovery time, and the post-surgical length of stay were observed. Blood amylase (AMY), C-reactive protein (CRP), plasma endotoxin (PLS), TNF-alpha, and IL-6 were detected before surgery, 12 h, 48 h, and 96 h after surgery.
RESULTSThe alleviation time of abdominal pain/distention, the gastrointestinal function recovery time, and the post-surgical length of stay were obviously shorter in the TM treatment group than those in the control group (P < 0.05). The recovery of AMY and CRP were better in the TM treatment group than in the control group at post-operative 48 h and 96 h (P < 0.05). The levels of LPS, TNF-alpha, and IL-6 were lower in the TM group than in the control group at post-operative 96 h (P < 0.05).
CONCLUSIONTM showed better clinical efficacy and could significantly decrease the post-surgical length of stay. post-ERCP pancreatitis; integrative medicine; Tongfu Mixture