A Case of Pernicious Anemia with Positive Anti Intrinsic Factor Antibody and Antiparietal Cell Antibody.
- Author:
Rok Yun LEE
1
;
Young Suk PARK
;
Tae Ho HAN
;
Jo Young CHOI
;
Seung Sik KANG
;
Soo Jong PARK
;
Jung Ae LEE
;
Sung Tae CHO
;
Jae Myung LEE
;
Duk Jae SHUN
;
Ji Young JUNG
;
Chan Jeoung PARK
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
- Publication Type:Case Report
- Keywords:
Megaloblastic anemia;
Pernicious anemia;
cobalamin deficiency
- MeSH:
Anemia;
Anemia, Megaloblastic;
Anemia, Pernicious*;
Arm;
Bone Marrow;
Female;
Foot;
Gingiva;
Hemorrhage;
Humans;
Hypesthesia;
Intrinsic Factor*;
Middle Aged;
Nausea;
Neurologic Examination;
Oral Ulcer;
Paresthesia;
Schilling Test;
Tongue;
Vitamin B 12;
Vomiting
- From:Korean Journal of Medicine
1997;52(4):570-574
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We present a case of pernicious anemia without history of operation in 52 year old female. She suffered from oral ulcer, gum bleeding, nausea, vomiting, and beefy tongue. She had dysesthesia on the both arm and foot, and hypesthesia of global and stocking type by neurologic examination. Laboratory findings were as follows: serum cobalamin 9.1 pg/mL (normal range: 180-710pg/mL), anti intrinsic factor antibody (strong positive), antiparietal cell Antibody 1:10 (positive), first stage of Schilling test (1.4%). The findings of peripheral blood and bone marrow were compatible with megaloblastic anemia. We report a case of pemicious anemia with positive anti intrinsic factor antibody and antiparietal cell antibody.
