Relationship between fetal growth restriction and ovarian reserve in adulthood.
- Author:
Ping PENG
1
;
Chunling MA
;
Changlan YE
;
Shumei WAN
;
Yanling ZHANG
;
Wei TENG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Anti-Mullerian Hormone; blood; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Fetal Growth Retardation; Follicle Stimulating Hormone; blood; Humans; Inhibins; blood; Menstrual Cycle; Ovarian Follicle; physiology; Ovarian Reserve; Prospective Studies; Young Adult
- From: Journal of Southern Medical University 2014;34(8):1217-1219
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between fetal growth restriction and decreased ovarian reserve (DOR) in adulthood to screen high-risk population for early interventions.
METHODSForty-four patients with FGR and 88 normal women aged 18-40 years were enrolled. All the subjects were examined for serum levels of follicle-stimulating hormone (FSH), inhibin B (INH-B), and anti-mullerian hormone (AMH) using enzyme-linked immunosorbent assay method in the first 3-5 days of the menstrual cycle, and the counts of antrum ovarian follicle were detected by transvaginal or transabdominal ultrasonography.
RESULTSThe serum levels FSH, INHB, AMH, and AFC in FGR group differed significantly from those in the control group (P<0.05).
CONCLUSIONFGR will affect reproductive endocrine function in adulthood to cause a decreased ovarian reserve.