Clinical observation of the efficacy of MEBO in the treatment of burn patients with burn area over 50% TBSA.
- Author:
Yong-cai HU
1
;
Cai-sheng OU
;
Ze-chun HUANG
;
Xi-sheng XU
;
Zhi-xiang LI
;
Liang-ying LUO
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Bacteria; isolation & purification; Bandages; Burns; drug therapy; microbiology; pathology; Child; Child, Preschool; Female; Humans; Infant; Injury Severity Score; Male; Middle Aged; Phytotherapy; Silver Sulfadiazine; therapeutic use; Treatment Outcome; Wound Healing
- From: Chinese Journal of Burns 2006;22(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effectiveness of MEBO in the treatment of burn patients with burn area over 50% TBSA.
METHODSTwo hundred and ninety-eight patients hospitalized in our hospital from May of 1991 to December of 2003 with burn area over 50% TBSA, who had MEBO treatment before hospitalization, were enrolled in the study as the experiment (E) group. Another group of 300 burn patients with burn area over 50% TBSA that treated with SD-Ag cream were enrolled in the study as the control (C) group. Bacterial culture results, major changes in injury and mortality were compared between the two groups.
RESULTSThere were 1 506 bacteria strains isolated from wounds in E group, and 9 main changes in injury (1679 cases) occurred with 20.8% mortality in this group. There were 353 bacteria strains isolated, with occurrence of 9 changes in injury (518 cases) and 4.7% mortality in the SD-Ag group.
CONCLUSIONMEBO is much less effective for the treatment of the burn patients with large burn area compared with SD-Ag cream treatment.