Advances in the research of intestinal glutamine transporters.
- Author:
Wei WU
1
;
Xi PENG
2
Author Information
1. Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, China.
2. Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, China. Email: pxlrmm@163.com.
- Publication Type:Journal Article
- MeSH:
Amino Acid Transport System ASC;
Biological Transport;
Enterocytes;
Epithelial Cells;
metabolism;
pathology;
Glutamine;
metabolism;
Humans;
Intestine, Small;
metabolism
- From:
Chinese Journal of Burns
2014;30(2):171-174
- CountryChina
- Language:Chinese
-
Abstract:
Glutamine, the most abundant amino acid in bloodstream, is the preferred fuel source for enterocytes. Glutamine exerts its functions through the activity of its transporters, which are located in cytomembrane, to transport it into or out of intestinal epithelial cells. Intestine is the primary center for glutamine metabolism in the body. As ASCT2 and B(0)AT1 are the most important glutamine transporters in the intestine, it wound be helpful to gain the knowledge of the structure, function, and pathologic changes and control strategy of the two transporters in order to have a better understanding of the metabolism and function of glutamine.
