Progress of Experimental Research on Differentiation of Muscle-Derived Stem Cells into Haematopoietic Lineages in Vitro -Review.
10.7534/j.issn.1009-2137.2016.06.052
- Author:
Juan-Juan WANG
1
;
Xiao-Ning GAO
1
;
Shan-Shan CHEN
1
;
Pan-Pan ZHANG
1
;
Tao WANG
2
;
Hao-Ying DOU
3
Author Information
1. School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
2. School of Integrated Traditional Chinese and Western Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. E-mail: wangtao6112@163.com.
3. School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. E-mail: douhaoying11@126.com.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2016;24(6):1897-1900
- CountryChina
- Language:Chinese
-
Abstract:
Muscle-derived stem cells (MDSC) are a population of multipotent stem cells in the muscular tissue. It provide an excellent prospect of hemopathy treatment due to their superiorities, such as rich sources, convenient material resource and a high survival rate after transplantation and so on. However, there are great differences in sampling, separation, purification, and proliferation when MDSC were cultured in vitro. In addition, the proliferation conditions of the MDSC in vitro are yet unclear. The related regulatory mechanisms, which MDSC transformed into haematopoietic cells, need to be investigated. In this article, the experimental researches on the differentiation of MDSC into haematopoietic lineages are reviewed, the concrete problems discussed in this review are culture of MDSC in vitro, identification of MDSC, proleferation of MDSC, differention of MDSC in to hematopoietic lineages and so on.