Lead Exposure and Oxidative Stress in Coal Miners.

Zlatko Zimet; Marjan Bilban; Teja Fabjan; Kristina Suhadolc; Borut Poljšak; Joško Osredkar

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Lead Exposure and Oxidative Stress in Coal Miners.

Author: Zlatko ZIMET ¹ ; Marjan BILBAN ² ; Teja FABJAN ³ ; Kristina SUHADOLC ³ ; Borut POLJŠAK ⁴ ; Joško OSREDKAR ³
Author Information

1. National Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia.
2. Department of Public Health, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000 Ljubljana, Slovenia.
3. University Medical Centre Ljubljana, Institute of Clinical Chemistry and Biochemistry, Njegoševa 4, 1000 Ljubljana, Slovenia.
4. Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, 1000 Ljubljana, Slovenia.
Publication Type:Journal Article
MeSH: Adult; Coal Mining; Environmental Pollutants; toxicity; Humans; Isoprostanes; blood; Lead; blood; toxicity; Male; Occupational Exposure; Oxidative Stress; drug effects
From: Biomedical and Environmental Sciences 2017;30(11):841-845
CountryChina
Language:English
Abstract: We aimed to investigate the short-term correlation between blood lead levels and oxidative stress generation in coal miners. The study involved 94 male coal miners from the Velenje Coal mine, arranged into four groups: three groups according to the number of consecutive working days, and a fourth control group. Miners who worked for three consecutive days had higher blood levels of lead and 8-isoprostane than the control group (P < 0.001). Correlation between lead and 8-isoprostane was of medium strength (r = 0.512, P < 0.001). Short-term lead environmental exposure can potentially harmful and should be considered when formulating improvements in working processes.