Non-composite combined liver and intestinal allotransplantation.
- Author:
Ning LI
1
;
You-sheng LI
;
Yuan-xin LI
;
Wei-ming ZHU
;
Xiao-dong NI
;
Liang ZHU
;
Bin CAO
;
Wei-su LI
;
Kai LUO
;
Jie-shou LI
Author Information
- Publication Type:Case Reports
- MeSH: Adult; Humans; Intestines; transplantation; Liver Transplantation; Male; Short Bowel Syndrome; therapy; Transplantation, Homologous; methods; Treatment Outcome
- From: Chinese Journal of Surgery 2004;42(1):45-47
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo report the first case of non-composite combined liver and intestinal allotransplantation in China. The technical aspects of the case and pros and cons of such an approach versus composite technique were discussed.
METHODSThe patient suffered from short bowel syndrome and TPN-related liver damage. A non-composite technique was used in this case. During operation, the whole 380 cm intestine was transplanted with systemic drainage and aortic inflow, while the liver graft was placed in a piggyback fashion. Warm ischemic time of donor graft was 2 min and 30 seconds, and cold ischemic duration for intestinal and liver graft was 6 hours and 40 and 8 hours and 7 utes respectively. Postoperative immunosuppression management includes tacrolimus, methylprednisolone, MMF and Zenapax.
RESULTSThe recipient recovered smoothly with no evidence of rejection on days' follow up. Now he is maintained well on enteral nutrition.
CONCLUSIONNon-composite technique should be considered in adult recipients, especially those with a history of abdominal infections or multiple laparotomies.