Cardiomyocytes membrane channel currents and their dynamics.
- Author:
Lijun SHANG
1
;
Liqun SHANG
;
Yurong LI
Author Information
1. Preclinical Experiment Center, Fourth Military Medical University, Xi'an 710032.
- Publication Type:Journal Article
- MeSH:
Action Potentials;
Algorithms;
Calcium Channels;
physiology;
Computer Simulation;
Ion Channels;
physiology;
Membrane Potentials;
Models, Cardiovascular;
Myocytes, Cardiac;
physiology;
Potassium Channels;
physiology;
Sodium Channels;
physiology
- From:
Journal of Biomedical Engineering
2003;20(1):83-85
- CountryChina
- Language:Chinese
-
Abstract:
The mathematical models for simulation of cardiac sodium, potassium and calcium channel kinetics courses and currents were developed to simulate the properties of ionic currents and channel dynamic courses. With modifications of these models, it is possible to make them integrated for simulating the whole process of action potential, thus additional discussion on ionic mechanism could provide a theoretical foundation for further animal experiments and clinical applications.