The related research of tissue-engineered tendon in vivo.
- Author:
Shujiang ZHANG
1
;
Tingwu QIN
;
Zhiming YANG
Author Information
1. Department of Orthopedic Surgery, West China Hospital of Sichuan University, Chengdu 610041.
- Publication Type:Journal Article
- MeSH:
Animals;
Biocompatible Materials;
metabolism;
Biodegradation, Environmental;
Bioprosthesis;
Collagen;
metabolism;
Dogs;
Mice;
Rats;
Sheep;
Tendons;
Tissue Engineering
- From:
Journal of Biomedical Engineering
2003;20(1):139-142
- CountryChina
- Language:Chinese
-
Abstract:
Using tissue-engineered tendons to repair tendons and ligaments as well as functional reconstruction is the focus of nowadays researches. The scaffolds must be not only unharmful to health, but also easy for cells attachment, and be able to induce collagen deposition to form a neotendon with mechanic properties similar to those of normal tendon. In recent researches, it has been found that the mechanic properties of the implants change with the degrading and femdonizing of scaffolds. The relationships between collagen deposition, scaffolds degradation and mechanic properties of neotendon need to be defined more clearly.
