Change of leukocytic phagocytosis during repeat hemoperfusion with cross-linked agar beads entrapped attapulgite clay.
- Author:
Wei HUANG
1
;
Yu MA
;
Xiaolan YANG
;
Xianjue TANG
;
Changda SHU
Author Information
1. Chongqing University of Medical Sciences, Chingqing 400016.
- Publication Type:Journal Article
- MeSH:
Agar;
Animals;
Biocompatible Materials;
Hemoperfusion;
methods;
Leukocytes;
drug effects;
physiology;
Magnesium Compounds;
Male;
Materials Testing;
Microspheres;
Phagocytosis;
drug effects;
Rats;
Rats, Wistar;
Silicon Compounds
- From:
Journal of Biomedical Engineering
2003;20(2):302-304
- CountryChina
- Language:Chinese
-
Abstract:
The leukocytic phagocytosis rate and the index of phagocytosis of rats on cross-linked agar beads entrapped attapulgite clay (CAA) hemoperfusion were studied. The results revealed that the leukocytic phagocytosis rate and the index of phagocytosis descended significantly after 1 hour and rose gradually after 6 hours. Finally it reached the normal level after 48 hours. Hemoperfusion repeated two times gave similar results. In conclusion, the function of leukocytic phagocytosis declined temporarily during CAA hemoperfusion. Many times hemoperfusion will not notably affect the body's defense system of rats.
