Breviscapine listed on progress of new varieties and dosage form research.
- Author:
Li-Hua TIAN
;
Li-Zhong ZHAO
;
Jia GU
;
Jun CAI
;
Lei YU
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Brain Ischemia;
drug therapy;
Dose-Response Relationship, Drug;
Drugs, Chinese Herbal;
administration & dosage;
economics;
Flavonoids;
administration & dosage;
economics;
Humans
- From:
China Journal of Chinese Materia Medica
2014;39(19):3719-3722
- CountryChina
- Language:Chinese
-
Abstract:
Breviscapine, a flavone glucuronide, is a cardiovascular medicine extracted from a Chinese herb Erigeron breviscapinus. Modern pharmacological research shows breviscapine has a therapeutic effect on cardiovascular diseases such as cerebral thrombus,cerebral ischemia hemiparesis and platelet aggregation et al. However, its poor water solubility and low bioavailability in vivo severely restrict the clinical application. In this article, we reviewed the marketing preparations of breviscapine and its research progress on the new dosage forms.
