Flavonoids from root of Machilus wangchiana.
- Author:
Wei CHENG
;
Wen-Dong XU
;
Xiao-Na FAN
;
Jian-Gong SHI
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
Flavonoids;
chemistry;
Lauraceae;
chemistry;
Mass Spectrometry;
Molecular Structure;
Plant Roots;
chemistry
- From:
China Journal of Chinese Materia Medica
2014;39(19):3794-3797
- CountryChina
- Language:Chinese
-
Abstract:
Twelve flavonoids were isolated from an ethanol extract of Machilus wangchiana by a combination of various chromatographic techniques including column chromatography over silica gel and Sephadex LH-20 and reversed-phase flash chromatography and HPLC. Their structures were identified by spectroscopic data analysis (IR, MS, and NMR) as (+)-catechin (1), (-)-epicatechin (2), 3'-O-methyl-(+)-catechin (3), 3'-O-methyl-(-)-epicatechin (4), 3, 5, 7, 2', 5'-pentahydroxy flavan (5), (-)-naringenin (6), (-)-eriodictyol (7), (-)-liquiritigenin (8), (2R,3R)-(+)-dihydrokaempferol (9), (2R,3S)-(-)-dihydro- kaempferol (10), (2R, 3R)-(+)-taxifolin (11), and quercetin (12). Compounds 1-10 are isolated from the genus Machilus for the first time.
