Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one.
- Author:
Han CHEN
;
Dan-Qian CHEN
;
Quan-Fu LI
;
Peng-Fei LI
;
Hua CHEN
;
Ying-Yong ZHAO
- Publication Type:Journal Article
- MeSH:
Animals;
Cholestenones;
chemistry;
pharmacokinetics;
pharmacology;
Drugs, Chinese Herbal;
chemistry;
pharmacokinetics;
pharmacology;
Humans
- From:
China Journal of Chinese Materia Medica
2014;39(20):3905-3909
- CountryChina
- Language:Chinese
-
Abstract:
Ergosta-4,6,8(14),22-tetraen-3-one (ergone) is one of main components in many medicinal fungi. Ergone has been reported to possess the activities of diuresis, cytotoxicity, antitumor, immunosuppression, as well as treatment of chronic kidney disease. According to reported literatures, an overview of spectroscopy characteristics, content determination, pharmacological activity and pharmacokinetics, etc. for ergone is presented in this review. Furthermore, the present review can provide a certain reference value for the further study and development of ergone.
