Alkaloids from roots and stems of Litsea cubeba.
- Author:
Shui-Ying ZHANG
;
Qiang GUO
;
Yuan CAO
;
Yuan ZHANG
;
Xiao-Li GAO
;
Peng-Fei TU
;
Xing-Yun CHAI
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Litsea;
chemistry;
Molecular Structure;
Plant Roots;
chemistry;
Plant Stems;
chemistry;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2014;39(20):3964-3968
- CountryChina
- Language:Chinese
-
Abstract:
A phytochemical investigation on the roots and stems of Litsea cubeba led to the isolation of seven isoquinolone alkaloids. By spectroscopic analysis and comparison of their 1H and 13C-NMR data with those in literatures, these alkaloids were identified as (+)-norboldine (1), (+)-boldine (2), (+)-reticuline (3), (+)-laurotetanine (4), (+)-isoboldine (5), (+)-N-methyl-laurotetanine (6), and berberine (7), respectively. Among them, 7 was isolated from the genus for the first time. The evaluation of these compounds showed weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells.
