Study on secondary metabolites of endophytic fungi Penicillium polonicum.
- Author:
Jing LIU
;
Guang-Zhi DING
;
Lei FANG
;
Shi-Shan YU
- Publication Type:Journal Article
- MeSH:
Biological Factors;
chemistry;
metabolism;
Endophytes;
chemistry;
isolation & purification;
metabolism;
Fabaceae;
microbiology;
Fermentation;
Penicillium;
chemistry;
isolation & purification;
metabolism;
Secondary Metabolism
- From:
China Journal of Chinese Materia Medica
2014;39(20):3974-3977
- CountryChina
- Language:Chinese
-
Abstract:
The PDB culture medium was selected to ferment the endophyte strain, and the secondary metabolites of endophytic fungi Penicillium polonicum were studied. Combined application of Sephadex LH-20, ODS and HPLC chromatographies over the ethyl acetate extract of the fermented culture led to the isolation of 6 compounds. By spectral methods, the structures were elucidated as [3, 5-dihydroxy-2-(7-hydroxy-octanoyl)]-ethylphenylacetate (1), (3, 5-dihydroxy-2- octanoyl)-ethyl phenylacetate (2), (5, 7-di- hydroxy-9-heptyl)-isobenzo pyran-3-one (3), 3-(hydroxymethyl) 4-(1E)-1- propen-1-yl-(1R, 2S, 5R, 6S)-7-oxabicyclo [4.1.0] hept-3-ene-2, 5-diol (4), (E)-2-methoxy-3-(prop-1-enyl) phenol (5) and p-hydroxylphenylethanol (6).
