Individual patient data meta-analysis is needed in Chinese medical research.
10.1007/s11655-014-1852-0
- Author:
Shi-Yan YAN
1
;
Li-Yun HE
;
Bao-Yan LIU
Author Information
1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Humans;
Patients
- From:
Chinese journal of integrative medicine
2014;20(11):805-811
- CountryChina
- Language:English
-
Abstract:
Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data (APD) from published articles. Individual patient data (IPD) meta-analysis, as the gold standard of systematic review, is a possible alternative in this context. However, the publications relative to IPD meta-analyses are still rare compared with the traditional ones, especially in the research oriented to Chinese medicine (CM). In this article, the strengths and detailed functioning of IPD meta-analysis are described. Furthermore, the need for IPD meta-analysis to assess the treatments based on CM was also discussed. Compared with the traditional APD meta-analysis, the IPD meta-analysis might give a more accurate and unbiased assessment and is worth to be recommended to CM researchers.
