Clinical characteristics of abnormal savda syndrome type in human immunodeficiency virus infection and acquired immune deficiency syndrome patients: A cross-sectional investigation in Xinjiang, China.

Mi-ji-ti Peierdun; Wen-xian Liu; Ai-ze-zi Renaguli; Amat Nurmuhammat; Xiao-chun LI; Ka-ha-er Gulibaier; Wu-la-mu Ainivaer; Upur Halmurat

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Clinical characteristics of abnormal savda syndrome type in human immunodeficiency virus infection and acquired immune deficiency syndrome patients: A cross-sectional investigation in Xinjiang, China.

Author: Mi-ji-ti PEIERDUN ¹ ; Wen-xian LIU ² ; Ai-ze-zi RENAGULI ² ; Amat NURMUHAMMAT ² ; Xiao-chun LI ³ ; Ka-ha-er GULIBAIER ³ ; Wu-la-mu AINIVAER ³ ; Upur HALMURAT ⁴
Author Information

1. Department of Epidemiology and Biostatistics, Xinjiang Medical University, Urumqi, 830011, China.
2. School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China.
3. Xinjiang Uighur Autonomous Region the Sixth People's Hospital, Urumqi, 840013, China.
4. School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China. halmurat@263.net.
Publication Type:Journal Article
Keywords: abnormal savda syndrome; depression; human immunodeficiency virus infection and acquired immune deficiency syndrome; symptoms; traditional Uighur medicine
MeSH: Acquired Immunodeficiency Syndrome; diagnosis; Adult; CD4 Lymphocyte Count; China; ethnology; Cross-Sectional Studies; Female; HIV Infections; diagnosis; Humans; Male; Medicine, Traditional; Middle Aged; Surveys and Questionnaires
From: Chinese journal of integrative medicine 2015;21(12):895-901
CountryChina
Language:English
Abstract:
OBJECTIVETo investigate the distribution of abnormal hilit syndromes in traditional Uighur medicine (TUM) among human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) patients, and to find out the clinical characteristics of abnormal savda syndrome type HIV/AIDS patients.
METHODSBetween June and July in 2012, 307 eligible HIV/AIDS patients from in-patient department and out-patient clinics of Xinjiang Uighur Autonomous Region the Sixth People's Hospital in Urumqi were investigated. TUM syndrome differentiation was performed by a senior TUM physician. Each participant completed a Sign and Symptom Check-List for Persons Living with HIV/AIDS (SSC-HIV) questionnaire. Depression was evaluated by using Hamilton Rating Scale for Depression Questionnaire. Blood specimen was collected from each participant to test the levels of blood chemicals.
RESULTSOf 307 HIV/AIDS patients, 189 (61.6%) were abnormal savda syndrome type, 118 (38.4%) were non-abnormal-savda syndrome type. Mean CD4 counts of abnormal savda syndrome type patients was (227.61±192.93) cells/µL, and the prevalence of anemia, thrombocytopenia, and elevated cystatin C were 49.7%, 28.6%, and 44.7%, which were significantly higher than those in the non-abnormal-savda syndrome type patients (26.3%, 16.0% and 25.0%,P<0.05). In addition, depression (79.9%) and HIV/AIDS-related symptoms such as fatigue (42.3%), back aches (40.7%), lack of appetite (33.9%), night sweats (31.7%) were more common among abnormal savda syndrome patients (P<0.05).
CONCLUSIONAbnormal savda syndrome is the dominant syndrome among HIV/AIDS patients, and they present a more sever clinical manifestation.