Chemical agents modulating bacterial biofilm formation and development.

Author: Xingyu LIU ¹ ; Xuwen XIANG ¹ ; Hui TAO ¹ ; Zining CUI ¹ ; Lianhui ZHANG ¹
Author Information

1. State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangzhou 510642, Guangdong, China.
Publication Type:Journal Article
Keywords: biofilm; dispersal; inhibit; natural products; signaling molecules; structure-activity relationship analysis
From: Chinese Journal of Biotechnology 2017;33(9):1433-1465
CountryChina
Language:Chinese
Abstract: Biofilm is a bacterial lifestyle ubiquitously in natural environments. Bacterial biofilm leads to drug resistance, a main reason why many infectious diseases are difficult to control. Due to the prominent points of biofilms implicated in infectious disease and the spread of multi-drug resistance, it is urgent to discover new antibacterial agents that can regulate biofilm formation and development. This review introduces chemical agents that could modulate bacterial biofilm formation and development.