Cathepsin S in pathogenesis of neurological diseases.
- Author:
Da-Ming WANG
1
;
Jian-Ren LIU
;
Hao-Yu HU
;
Guo-Ping SHI
Author Information
1. Department of Neurology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
- Publication Type:Journal Article
- MeSH:
Alzheimer Disease;
physiopathology;
Astrocytoma;
physiopathology;
Brain Neoplasms;
physiopathology;
Cathepsins;
physiology;
Humans;
Intracranial Arteriosclerosis;
physiopathology
- From:
Journal of Zhejiang University. Medical sciences
2008;37(4):422-426
- CountryChina
- Language:Chinese
-
Abstract:
Cathepsin S, one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. Those functions are closely associated with the pathogenesis of various neurological diseases. It would be beneficial to elucidate the role of Cathepsin S in the pathogenesis of various neurological diseases.