Platelet count of peripheral blood is associated with invasion and metastasis of esophageal carcinoma.
- Author:
Xin-chun YU
1
;
Shan-shui WU
;
Xiao-qing LU
;
Li-ming SHENG
;
Ya-guo HU
;
Jian ZHAO
;
Juan-mei LI
;
Hai-yan SHAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Blood Platelets; cytology; Carcinoma, Squamous Cell; blood; pathology; Case-Control Studies; Esophageal Neoplasms; blood; pathology; Female; Humans; Lymphatic Metastasis; Male; Middle Aged; Platelet Count
- From: Journal of Zhejiang University. Medical sciences 2009;38(2):170-173
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the association between the platelet count of peripheral blood and clincopathologic parameters of esophageal carcinoma.
METHODSPlatelets of peripheral blood were measured in 415 cases of esophageal carcinoma and 325 healthy subjects as control. The correlation of platelet counts and clinicopathological features of cancer was analyzed.
RESULTPlatelet count in patients with esophageal carcinomas (286+/-88)x10(9)/L was significantly higher than that in the control subjects [(204+/-114)x10(9)/L, P<0.05 ]. Increased platelet counts (>300 x 10(9)/L) was significantly associated with tumor infiltration and lymph node metastasis in patients with esophageal cancer (P<0.05).
CONCLUSIONPlatelet count of peripheral blood might be associated with the development and progression of esophageal cancer.
