Clinical data mining by exploring public MIMIC-II intensive care database.
- Author:
Jian WANG
;
Zhengbo ZHANG
;
Weidong WANG
;
Liang PAN
;
Xiaoke CHAI
- Publication Type:Journal Article
- MeSH:
Blood Pressure;
Circadian Rhythm;
Critical Care;
Data Mining;
Databases, Factual;
Heart Rate;
Humans;
Medical Informatics
- From:
Chinese Journal of Medical Instrumentation
2014;38(6):402-406
- CountryChina
- Language:Chinese
-
Abstract:
This paper introduces a free and publicly open ICU database: multi-parameter intelligent monitoring in intensive care II: MIMIC-II, which has been built up and maintained by the laboratory of computational physiology at the Massachusetts Institute Technology, Beth Israel Deaconess Medical Center and Philips Healthcare over the past decade. This paper briefly introduces its infrastructure, implementation and applications in clinical studies. Clinical study pertaining to circadian variation in heart rate and blood pressure during sepsis is shown as a typical example of research performed with MIMIC-II. In this study, it was found there was significant difference in circadian variation in both heart rate and blood pressure between survival and non-survival groups in septic patients. This study tackled several important techniques necessary for the investigation of the circadian rhythm.