Study on cytotoxicity tests of medical devices based on IC50.
- Author:
Chenghu LIU
;
Shifu WU
;
Li HOU
;
Xin WANG
;
Luanluan WANG
;
Yanping SHI
- Publication Type:Journal Article
- MeSH:
Equipment and Supplies;
adverse effects;
standards;
Inhibitory Concentration 50;
Toxicity Tests;
methods
- From:
Chinese Journal of Medical Instrumentation
2014;38(6):433-467
- CountryChina
- Language:Chinese
-
Abstract:
To discuss IC50 application in cytotoxicity tests of medical devices, we firstly investigated the vibrating condition and endpoint of MTT method specified in ISO 10993-5: 2009. Furthermore, we demonstrated the application of IC50 in the result evaluation of MTT method. The experimental results show that usage of IC50 in quantitative evaluation of MTT method is feasible.
