Phagocytic function of macrophage after partial splenectomy of rabbits using microwave tissue coagulation.
- Author:
Xinhua JU
1
;
Zhenlong XIA
;
Zhizhang WANG
;
Ying MA
;
Chengbing LI
Author Information
1. Department of General Surgery, The Second Affiliated Hospital of China Medical University, Shenyang 110004, China. juxinhuae@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Female;
Macrophages;
immunology;
Male;
Microwaves;
therapeutic use;
Phagocytes;
immunology;
Rabbits;
Regeneration;
immunology;
Spleen;
physiology;
Splenectomy;
methods
- From:
Journal of Biomedical Engineering
2005;22(6):1238-1240
- CountryChina
- Language:Chinese
-
Abstract:
The immune function of spleen after partial splenectomy (PSM) of rabbits was stuided using microwave tissue coagulation (MTC). Streptococcus pneumoniae suspension was injected into the ear veins of rabbits 4 weeks after they were subjected to partial splenectomy using microwave tissue coagulation (PSM) group and to sham operation (SO groups), respectively. India ink was given via portal vein. Residual spleen were resected and microscopic examinations were performed on spleen slices stained using HE to compare phagocytic functions of macrophage. Gradings of phagocytic function in macrophage were of no significant difference between PSM and SO groups (P > 0.05). Weights of spleens showed no significant difference between the two groups (P > 0.05). The phagocytic function of macrophage after PSM can be preserved well. The result of this experiment implies that splenic salvage using MTC is a clinically applicable method.
