Multi-centered clinical trial of Fufang Xuanju capsule for oligoasthenospermia.
- Author:
Hui JIANG
1
;
Xue-Jun SHANG
;
Jun GUO
;
Zheng LI
;
Lian-Ming ZHAO
;
Yong SHAO
;
Ping PING
;
Yu-Feng HUANG
;
Ji-Chuan ZHU
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Capsules; Drugs, Chinese Herbal; therapeutic use; Humans; Infertility, Male; drug therapy; Male; Oligospermia; drug therapy; Phytotherapy; Sperm Count; Sperm Motility; drug effects; Spermatozoa; cytology; drug effects; physiology; Treatment Outcome
- From: National Journal of Andrology 2008;14(8):755-758
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the efficacy of Fufang Xuanju Capsule in the treatment of oligoasthenospermia.
METHODSUsing a multi-centered, open and self-controlled clinical trial, we treated 120 patients with oligoasthenospermia, with Fufang Xuanju Capsule for 12 weeks, and evaluated the efficacy of the capsule with sperm concentration and vitality (a + b) as the primary and the number of grade a sperm, sperm motility (a + b + c) and semen volume as the secondary therapeutic indexes.
RESULTSA total of 107 patients accomplished the clinical trial. Compared with pre-treatment, sperm density, vitality and motility were significantly improved after 4, 8 and 12 weeks of Fufang Xuanju treatment (P < 0.01). At 12 weeks, sperm concentration was increased by 63.28%, with 73 cases (68.22%) restored to normal, sperm vitality by 63. 17%, with 39 (36.45%) restored to normal, sperm motility by 44.36%, with 77 (71.96%) restored to normal, and the semen volume by 18.13%.
CONCLUSIONFufang Xuanju Capsule can evidently improve the seminal quality of oligoasthenospermia patients.
