Flavone compound induces the apoptosis of prostate cancer cells.
- Author:
Li ZHANG
1
;
Xue-Jun SHANG
;
Yu-Feng HUANG
Author Information
1. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China. njust_zhangli@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Apoptosis;
drug effects;
Flavones;
pharmacology;
Humans;
Male;
Prostatic Neoplasms;
pathology;
Rats;
Tumor Cells, Cultured
- From:
National Journal of Andrology
2008;14(9):842-845
- CountryChina
- Language:Chinese
-
Abstract:
Flavone compound is a polyphenolic compound widely existing in plants and has an extensive biological activity. In recent years, it has been found to have a significant anti-cancer effect, as in combating cell proliferation, inducing cell apoptosis, interfering with cellular signal transduction, increasing the activity of the cancer repressor gene and inhibiting the expression of oncogene. This paper reviews the mechanism by which flavone compound, induces the apoptosis of prostate cancer cells.
