Comprehensive treatment of stage-lllb testicular non-seminomatous germ cell tumor: a case report and review of the literature.

Author: Jin-Bo CHEN ; Xiong-Bing ZU ; Lin QI ; Min-Feng CHEN
Publication Type:Case Reports
MeSH: Adult; Antineoplastic Combined Chemotherapy Protocols; therapeutic use; Combined Modality Therapy; Humans; Lymph Node Excision; methods; Male; Retrospective Studies; Testicular Neoplasms; therapy
From: National Journal of Andrology 2014;20(3):263-266
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the comprehensive treatment of stage-IIIb testicular non-seminomatous germ cell tumor (NSGCT) based on the chemotherapy with cisplatin, etoposide and bleomycin (BEP) and nerve-sparing laparoscopic retroperitoneal lymph node dissection (nsLRPLND).
METHODSWe reported a case of stage-IIIb testicular NSGCT, analyzed the clinical data and treatment methods and reviewed the relevant literature.
RESULTSThe patient underwent chemotherapy with etoposide (0. 18 g/d for the first 3 days), cisplatin (30 mg/d for the first 5 days), and bleomycin (30 mg/d on day 2, 9 and 16) for 3 cycles, followed by nsLRPLND. Both chemotherapy and surgery were successfully performed. The operation time was 175 min, with intraoperative blood loss of 50 ml, but no severe perioperative complications. No recurrence and distant metastasis were found during the 6-month follow-up after surgery.
CONCLUSIONThe comprehensive treatment based on BEP chemotherapy and nsRPLND can be used as an option for stage-IIIb testicular NSGCT.