Numb-Chin Syndrome in Malignant Hematologic Diseases.
- Author:
Seung Han SUK
1
;
Il Nam SUNWOO
;
Seung Min KIM
;
Sung Ju LEE
;
Jee Sook LEE
;
Jee Sook HAHN
;
Yun Woong KO
Author Information
1. Department of Neurology, College of Medicine, Yonsei University, Korea.
- Publication Type:Case Report
- MeSH:
Diagnosis;
Early Diagnosis;
Hematologic Diseases*;
Leukemia;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive;
Lymphoma;
Prognosis
- From:Journal of the Korean Neurological Association
1992;10(1):89-92
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
'Num-chin syndrome', isolated mental neuropathy, is a rare manifestaion of malignant hernatologic diseases, but important sign for early diagnosis and prediction of clinical course and prognosis. Here we report 7 cases of numb-chin syndrome; one in leukemic transformation of malignant lymphoma, one in blastic crisis of chronic myelogenous leukemia and 5 in acute leukemia Two cases of acute leukemia revealed the 'numb-chin sign' in early course of disease before the diagnosis of leukemia and other three in aggravating state of acute leukemia. The therapeutic response and prognosis was poor and 5 cases expired in a few months.
