Single nucleotide polymorphisms and prostate cancer.
- Author:
Chao MA
;
Chun-Xiao LIU
;
Peng HUANG
- Publication Type:Journal Article
- MeSH:
Humans;
Male;
Polymorphism, Single Nucleotide;
Prostatic Neoplasms;
genetics
- From:
National Journal of Andrology
2014;20(8):738-742
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer is a common malignancy that affects men's health in the Western countries. Single nucleotide polymorphisms (SNPs), as the third generation of genetic markers, can influence the development, progression, and prognosis of prostate cancer. The same SNP may be related differently with prostate cancer among different races. This paper describes the relationship between SNPs and prostate cancer according to their related genes. SNPs can predict the risk of prostate cancer as well as the possible adverse reactions in its treatment, but at present they do have some limitations.
