OBJECTIVETo analyze the correlation between 102 hypertension patients and northwest dryness syndrome (NDS).

METHODSIn the treatment group recruited were 102 hypertension patients from hospitals with the level above the county level in Hotan, Turpan, Hami, Yili, and Urumqi from August to December 2009. Another 173 sub-healthy subjects were recruited as the control group. The incidence rate and the NDS integral were compared between the two groups. The correlation analysis and canonical correlation analysis were performed between Chinese medical integral in the treatment group and main and complicated syndromes integrals of NDS.

RESULTSThe incidence rate of NDS was 31.37% (32/102) in the treatment group and 16.76% (29/102) in the control group, showing statistical difference (chi2 = 7.934, P<0.01). The total integral of NDS was higher in the treatment group than in the control group (P<0.05). Of them, the integrals of Fei-orifice obstruction induced dry syndrome (FOOIDS), Xin-Shen yin deficiency syndrome (XSYDS), and Pi-Wei damp accumulation syndrome (PWDAS) were higher in the treatment group than in the control group (P<0.05), with the most obvious shown in XSYDS. Various syndromes of hypertension were strongly correlated with main and complicated syndromes of NDS (P<0.01). Of them, the strongest correlation was shown between yin-yang deficiency syndrome (YYDS) and NDS (r=0.864, P<0.01), followed by yin deficiency and yang hyperactivity syndrome (r=0.765, P<0.01). The standard canonical correlation coefficient was the highest in YYD (r=0.5599) and the independent variable was the highest in PWDAS (r=0.4191).

CONCLUSIONSDNS was the contaminant state for most hypertension patients in Xinjiang region, with XSYDS as the most outstanding manifestation. DNS could aggravate the Chinese medical integrals of hypertension. YYDS was closest correlated with DNS. PWDAS showed most significant effects on the syndrome integral of hypertension. YYDS and PWDAS were decisive factors between hypertension and DNS.