Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies.
- Author:
Shi-ping LUH
1
;
Chi-huei CHIANG
Author Information
1. Department of Surgery, Chung-Shan Medical University Hospital, 402 Taichung, Taiwan, China. luh572001@yahoo.com.tw
- Publication Type:Journal Article
- MeSH:
Acute Disease;
Animals;
Cell Transplantation;
Genetic Therapy;
Humans;
Lung;
physiopathology;
Lung Injury;
Respiration, Artificial;
Respiratory Distress Syndrome, Adult;
etiology;
physiopathology;
therapy
- From:
Journal of Zhejiang University. Science. B
2007;8(1):60-69
- CountryChina
- Language:English
-
Abstract:
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from various processes that directly or indirectly injure the lung. Extensive investigations in experimental models and humans with ALI/ARDS have revealed many molecular mechanisms that offer therapeutic opportunities for cell or gene therapy. Herein the present strategies and future perspectives of the treatment for ALI/ARDS, include the ventilatory, pharmacological, as well as cell therapies.
