Evaluation of organ distribution of microcystins in the freshwater phytoplanktivorous fish Hypophthalmichthys molitrix.
- Author:
Hang-jun ZHANG
1
;
Jian-ying ZHANG
;
Ye HONG
;
Ying-xu CHEN
Author Information
1. School of Environmental and Resource Sciences, Zhejiang University, Hangzhou, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Carps;
metabolism;
parasitology;
Fresh Water;
analysis;
parasitology;
Microcystins;
metabolism;
Organ Specificity;
Phytoplankton;
metabolism;
Risk Assessment;
methods;
Risk Factors;
Tissue Distribution;
Water Pollutants, Chemical;
analysis
- From:
Journal of Zhejiang University. Science. B
2007;8(2):116-120
- CountryChina
- Language:English
-
Abstract:
To evaluate the public health risk of exposure to microcystins in fish food in China, the distribution pattern of microcystin-LR and microcystin-RR in various organs (liver, intestine, kidney, muscle and lipid) of the dominant freshwater phytoplanktivorous fish Hypophthalmichthys molitrix in Hangzhou, China's Tiesha River was investigated with the method of HPLC-ESI-MS analysis. The distribution of microcystins was different in the fish organs and the major total microcystins (microcystin-LR and microcystin-RR) were present in the intestines (6.49 micro g/g fresh weight), followed by the livers (4.52 micro g/g fresh weight) and the muscles (2.86 micro g/g fresh weight). Microcystins were detected in kidneys (1.35 micro g/g fresh weight), but not detected in lipid. The results suggested that the mean daily intake from fish was 0.03 micro g/kg body weight which was very close to the recommended WHO tolerable daily intake (TDI) level of 0.04 micro g/kg body weight per day, and local people were warned they may have health risk if they consumed fish from the river.
