Pathological character and treatment of epithelial-myoepithelial carcinoma of salivary gland.
- Author:
Hao LI
1
;
Guo-hao WU
;
Fu-jin CHEN
;
Quan ZHANG
;
Mao-wen WEI
;
Wen-kuan CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Carcinoma; pathology; therapy; Female; Humans; Male; Middle Aged; Myoepithelioma; pathology; therapy; Retrospective Studies; Salivary Gland Neoplasms; pathology; therapy; Salivary Glands; pathology
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(4):281-283
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo review and evaluate pathologic features and treatment of epithelial-myoepithelial.
METHODSRetrospectively reviewed 14 cases' pathological and clinical materials of epithelial-myoepithelial carcinoma of salivary gland. Eight cases origine from parotid gland, 2 cases from hard palate, 3 cases from submandibular gland and 1 case from nasal cavity. Three cases were performed induction chemotherapy preoperation. One case had palliative radiotherapy. Thirteen cases were performed radical surgery and 6 cases had radiotherapy postoperation.
RESULTSTumor arisen mostly from parotid gland and neck lymph node metastasis rate was 14.28% (2/14). The survival rate was calculated with Kaplan-Meier method. The overall 3-, 5- and 10-year survival rate were 67.20%, 45.49% and 17.06%. Its histological characteristics were inner layer composed by adenoid cells and outer layer composed by myoepithelial cells. Immunohistochemical exam show cytokeratin, S-100 and actin reaction positive.
CONCLUSIONSEpithelial-myoepithelial carcinoma easily develops recurrence. It is sensitivity to radiotherapy and chemotherapy to some extent. It is suitable to adopt surgical treatment as primary modality combined with other therapies.
