Sesquiterpenes from stem of Schisandra glaucescens.
- Author:
Pei-Pei ZHANG
1
;
Sha-Sha GAO
;
Tian-Tian ZHANG
;
Jia-Chun CHEN
;
Hong-Quan DUAN
;
Jin-Bo FANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; chemistry; isolation & purification; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Stems; chemistry; Schisandra; chemistry; Sesquiterpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2012;37(22):3426-3429
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents from Schisandra glaucescens.
METHODThe chemical constituents were separated and purifed with silica gel, gel column chromatography preparative HPLC, and their structures were identified by such spectral methods as MS and NMR.
RESULTTwelve compounds were separated from petroleum ether fractions, and identified as t-cadinol (1), alpha-cadinol (2), torreyol (3), (+)-ent-epicubenol (4), ent-T-muurolol (5), (-)-15-hydroxycalamenene (6), (-)-cubebol (7), 4-epi-cubebol (8), caryophyllenol-I (9), caryophyllenol-II (10), oxyphyllenodiols A (11), caryolane-1,9/3-diol (12).
CONCLUSIONCompounds 4, 6-12 were separated from the genus for the first time, while compounds 1-12 were separated from this plant for the first time.
