Chemical constituents of Acorus calamus.
- Author:
Di QIAO
1
;
Li-She GAN
;
Jian-Xia MO
;
Chang-Xin ZHOU
Author Information
- Publication Type:Journal Article
- MeSH: Acorus; chemistry; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; chemistry; isolation & purification; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Roots; chemistry; Spectrometry, Mass, Electrospray Ionization
- From: China Journal of Chinese Materia Medica 2012;37(22):3430-3433
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents contained in Acorus calamus.
METHODThe chemical constituents were separated and purified by various chromatographic methods including silica gel, ODS, HPLC and Sephadex LH-20, and their structures were identified on the basis of analysis on spectroscopic data.
RESULTTen compounds were separated from A. calamus and identified as 1beta, 4beta, 7alpha-trihydroxyeudesmane (1), bullatantriol (2), teuclatriol (3), threo-1', 2'-dihydroxyasarone (4), erythro-1', 2'-dihydroxyasarone (5), (+)-de-4'-O-methyleudesmin (6), (+)-de-4'-0-methylmagnolin (7), (+)-eudesmin (8), (+)-magnolin (9) and beta-sitosterol (10), respectively.
CONCLUSIONCompounds 1-2,4-9 were separated from this plant for the first time. Specifically, compounds 1-2,6-9 were obtained from Acorus genus for the first time.