Stable life predection for Psoralea corylifolia by initial average rate stability test.
- Author:
Jin-Feng WEI
1
;
Zhi-Ping XUE
;
Jie LIU
;
Wen-Yi KANG
Author Information
- Publication Type:Journal Article
- MeSH: Drug Stability; Psoralea; chemistry; Temperature
- From: China Journal of Chinese Materia Medica 2012;37(21):3176-3178
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the total content change of psoralea and isopsoralea in Psoralea corylifolia under different temperature, and predict its term of validity by initial average rate stability test in order to provide the basis for assessing its quality.
METHODThe reaction rate constant K was replaced by initial velocity V. According to Arrhenius rule, storage period was obtained at room temperature.
RESULTThe stable life of P. corylifolia has been determined as 0.53 years.
CONCLUSIONThe high temperature is not conducive to the stability of the P. corylifolia, which need to store in a dark and cool place.