Chemical constituents of Psammosilene tunicoides and bacteriostatic activity.
- Author:
Long WANG
1
;
Xiao-Jian GONG
;
Xin ZHOU
;
Chun XIAN
;
Shi-Lin YANG
;
Zhan-Nan YANG
Author Information
- Publication Type:Journal Article
- MeSH: Anti-Bacterial Agents; chemistry; isolation & purification; pharmacology; Bacteria; drug effects; Caryophyllaceae; chemistry; Drugs, Chinese Herbal; chemistry; isolation & purification; pharmacology
- From: China Journal of Chinese Materia Medica 2012;37(23):3577-3580
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents and bacteriostatic activity of Psammosilene tunicoides.
METHODSuch methods as silica gel column chromatography and gel column chromatography were adotped separate and purify the compounds, and their structures were indentified on the basis of their spectral data and physicochemical properties.
RESULTTen compounds were separated from ethanol extracts and identified as methyl-4-hydroxybenzoate (1), N-methylsaccharin (2), 3-hydroxy-4-methoxybenzoic acid (3), germanicol (4), tricosanoic acid (5), octacosane (6), amber acid (7), succinic acid (8), stellarine A (9), and oleanane-12-ene-3alpha, 16alpha-two hydroxy-23,28-acid (10).
CONCLUSIONAll compounds except compound 10 were separated from P. tunicoides for the first time. Compounds 8 and 9 showed the bacteriostatic activity to a certain extent.
