Clinical predictors of cytomegalovirus infection after liver transplantation.
- Author:
Jiantao KOU
1
;
Jiqiao ZHU
1
;
Hua FAN
1
;
Jun MA
1
;
Ping LI
1
;
Dongdong HAN
1
;
Qiang HE
2
;
Email: HEQIANG349@SINA.COM.
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Beijing; Cytomegalovirus Infections; diagnosis; End Stage Liver Disease; diagnosis; Female; Graft Rejection; Humans; Liver Transplantation; adverse effects; Logistic Models; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; virology; Reoperation; Retrospective Studies; Severity of Illness Index
- From: Chinese Journal of Surgery 2015;53(4):270-273
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical predictors of cytomegalovirus (CMV) infection after liver transplantation.
METHODSThe clinical data of 182 patients (146 male and 36 female with a mean age of (50 ± 7) years) receiving liver transplantation in Beijing Chaoyang Hospital between January 2004 and December 2008 were retrospectively analyzed.All patients were divided into two groups, namely the CMV infection group (n=24) and the control group (n=158). Logistic regression was used to identify the predictive factors of postoperative CMV infection.
RESULTSAccording to univariate analysis results, the factors for CMV infection were acute liver failure (P=0.032), MELD score ≥ 30 (P=0.001), liver retransplantation (P=0.002), acute rejection (P=0.000) and delayed graft function (P=0.022). According to multi-analysis results, MELD score ≥ 30 (P=0.037, 95%CI:1.194-271.461) and acute rejection (P=0.033, 95%CI:1.179-51.863) were proved to be independent predictors by multivariate analysis.
CONCLUSIONThe study indicates that MELD score ≥ 30 and acute rejection are the independent predictors of CMV infection.
